Social visual preference mediates the effect of cortical thickness on symptom severity in children with autism spectrum disorder.

ABSTRACT:

Background

Evidence suggests that there is a robust relationship between altered neuroanatomy and autistic symptoms in individuals with autism spectrum disorder (ASD). Social visual preference, which is regulated by specific brain regions, is also related to symptom severity. However, there were a few studies explored the potential relationships among brain structure, symptom severity, and social visual preference.

Methods

The current study investigated relationships among brain structure, social visual preference, and symptom severity in 43 children with ASD and 26 typically developing (TD) children (aged 2-6 years).

Results

Significant differences were found in social visual preference and cortical morphometry between the two groups. Decreased percentage of fixation

SUBMITTER: Chen J 

PROVIDER: S-EPMC10311909 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature