A preliminary study of the salivary microbiota of young male subjects before, during, and after acute high-altitude exposure.

ABSTRACT:

Background

The microbial community structure in saliva differs at different altitudes. However, the impact of acute high-altitude exposure on the oral microbiota is unclear. This study explored the impact of acute high-altitude exposure on the salivary microbiome to establish a foundation for the future prevention of oral diseases. Methods. Unstimulated whole saliva samples were collected from 12 male subjects at the following three time points: one day before entering high altitude (an altitude of 350 m, pre-altitude group), seven days after arrival at high altitude (an altitude of 4,500 m, altitude group) and seven days after returning to low altitude (an altitude of 350 m, post-altitude group). Thus, a total of 36 saliva samples were obtained. 16S rRNA V3-V4 region amplicon sequ

SUBMITTER: Zhou Q 

PROVIDER: S-EPMC10312199 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature