Distinct neural representations during a brain-machine interface and manual reaching task in motor cortex, prefrontal cortex, and striatum.

ABSTRACT: Although brain-machine interfaces (BMIs) are directly controlled by the modulation of a select local population of neurons, distributed networks consisting of cortical and subcortical areas have been implicated in learning and maintaining control. Previous work in rodent BMI has demonstrated the involvement of the striatum in BMI learning. However, the prefrontal cortex has been largely ignored when studying motor BMI control despite its role in action planning, action selection, and learning abstract tasks. Here, we compare local field potentials simultaneously recorded from the primary motor cortex (M1), dorsolateral prefrontal cortex (DLPFC), and the caudate nucleus of the striatum (Cd) while nonhuman primates perform a two-dimensional, self-initiated, center-out task under BMI control

SUBMITTER: Zippi EL 

PROVIDER: S-EPMC10312492 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature