Ontology highlight
ABSTRACT:
SUBMITTER: Sloutskin A
PROVIDER: S-EPMC10312617 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Sloutskin Anna A Itzhak Dekel D Vogler Georg G Ideses Diana D Alter Hadar H Shachar Hadar H Doniger Tirza T Frasch Manfred M Bodmer Rolf R Duttke Sascha H SH Juven-Gershon Tamar T
bioRxiv : the preprint server for biology 20230612
Transcription is initiated at the core promoter, which confers specific functions depending on the unique combination of core promoter elements. The downstream core promoter element (DPE) is found in many genes related to heart and mesodermal development. However, the function of these core promoter elements has thus far been studied primarily in isolated, <i>in vitro</i> or reporter gene settings. <i>tinman</i> (<i>tin</i>) encodes a key transcription factor that regulates the formation of the ...[more]