Predictive role of pretreatment skeletal muscle mass index for long-term survival of bladder cancer patients: A meta-analysis.

ABSTRACT:

Purpose

To identify the predictive role of pretreatment skeletal muscle mass index (SMI) for long-term survival of bladder cancer patients.

Methods

Several databases were searched for studies investigating the relationship between pretreatment SMI and prognosis in bladder cancer. The overall survival (OS) and cancer-specific survival (CSS) were defined as primary and secondary outcomes, respectively. Hazard ratios (HRs) and 95% confidence intervals (CIs) were combined.

Results

Nine studies involving 1476 cases were included. The results demonstrated that a lower pretreatment SMI was significantly related to poorer OS (HR = 1.56, 95% CI: 1.33-1.82, P<0.001) and subgroup analysis based on thresholds of SMI revealed similar results. Besides, pretreatment SMI was also obv

SUBMITTER: Yuan Q 

PROVIDER: S-EPMC10313011 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature