Association Between Ghrelin and Body Weight Trajectory in Individuals With Anorexia Nervosa.

ABSTRACT:

Importance

Individuals with anorexia nervosa maintain extremely low body weights despite elevations in the circulating orexigenic hormone ghrelin. Whether circulating levels of endogenous ghrelin are associated with weight gain in anorexia nervosa is unknown.

Objective

To examine the association between baseline ghrelin and future weight change in individuals with anorexia nervosa.

Design, setting, and participants

This prospective cohort study was conducted between April 1, 2014, and March 31, 2020, in the US. Girls and women aged 10 to 22 years were recruited from the greater Boston area from community and area treatment centers, enrolled, and followed up for 18 months. Statistical analyses were performed between January and August 2022.

Exposures

Presence or

SUBMITTER: Kim YR 

PROVIDER: S-EPMC10313149 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature