LncRNA AL161431.1 predicts prognosis and drug response in head and neck squamous cell carcinoma.

ABSTRACT:

Background

Long non-coding RNAs (lncRNAs) are increasingly recognized as essential players in various biological processes due to their interactions with DNA, RNA, and protein. Emerging studies have demonstrated lncRNAs as prognostic biomarkers in multiple cancers. However, the prognostic effect of lncRNA AL161431.1 in head and neck squamous cell carcinoma (HNSCC) patients has not been reported.

Methods

In the present study, we conducted a series of analyses to identify and validate the prognostic value of lncRNA AL161431.1 in HNSCC, which included differential lncRNAs screening, survival analysis, Cox regression analysis, time ROCanalysis, nomogram prediction, enrichment analysis, tumor infiltration of immune cells, drug sensitivity analysis, and quantitative real-time poly

SUBMITTER: Zhou M 

PROVIDER: S-EPMC10313201 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature