Correlation between hyperbilirubinemia risk and immune cell mitochondria parameters in neonates with jaundice.

ABSTRACT:

Purpose

To explore the correlation between mitochondria parameters of immune cells and hyperbilirubinemia risk in hospitalized neonates with jaundice.

Methods

This retrospective study included jaundiced neonates born between September 2020 and March 2022 at Shaoxing Keqiao Women & Children's Hospital. The neonates were divided into low, intermediate-low, intermediate-high, and high-risk groups according to the hyperbilirubinemia risk. The purpose parameters including percentage, absolute count, mitochondrial mass (MM), and single-cell MM (SCMM) of peripheral blood T lymphocytes detected by flow cytometry were collected.

Results

Finally, 162 neonates with jaundice (47, 41, 39, and 35 with low, intermediate-low, intermediate-high, and high-risk) were included. CD3⁺

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10313225 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature