Umbilical artery thrombosis and maternal positive autoimmune antibodies: two case reports and a literature review.

ABSTRACT:

Background

Previous studies have shown that abnormal increases in autoimmune antibodies in pregnant women may increase the risk of maternal thrombosis. However, at our hospital, two pregnant women presented with umbilical artery thrombosis and positive maternal autoantibodies were detected in both, which led us to consider whether maternal autoantibodies also played a role in umbilical artery thrombosis.

Case presentation

Case 1: Fetal ultrasound of a 34-year-old pregnant woman at 30⁺⁴ weeks gestation showed two umbilical arteries, with an inner diameter of approximately 0.15 cm for the smaller was artery. However, only a single umbilical artery blood flow signal was detected. Due to fetal distress, which was noted on abnormal cardiotocography and Doppler ultrasou

SUBMITTER: Li X 

PROVIDER: S-EPMC10313525 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature