Cortical Deficits are Correlated with Impaired Stereopsis in Patients with Strabismus.

ABSTRACT: In this study, we explored the neural mechanism underlying impaired stereopsis and possible functional plasticity after strabismus surgery. We enrolled 18 stereo-deficient patients with intermittent exotropia before and after surgery, along with 18 healthy controls. Functional magnetic resonance imaging data were collected when participants viewed three-dimensional stimuli. Compared with controls, preoperative patients showed hypoactivation in higher-level dorsal (visual and parietal) areas and ventral visual areas. Pre- and postoperative activation did not significantly differ in patients overall; patients with improved stereopsis showed stronger postoperative activation than preoperative activation in the right V3A and left intraparietal sulcus. Worse stereopsis and fusional control were

SUBMITTER: Xi S 

PROVIDER: S-EPMC10313621 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature