Longitudinal Associations Between Reward Responsiveness and Depression Across Adolescence.

ABSTRACT:

Objective

Lower neural response to reward predicts subsequent depression during adolescence. Both pubertal development and biological sex have important effects on reward system development and depression during this period. However, relations among these variables across the transition from childhood to adolescence are not well characterized.

Method

Depressive symptoms, pubertal status, and the reward positivity (RewP) event-related potential component, a neural indicator of reward responsivity, were assessed in 609 community-recruited youth at 9, 12, and 15 years of age. Structural equation modeling was used to examine concurrent and prospective relations within and between depression and reward responsiveness as well as the influence of pubertal status and biological sex

SUBMITTER: Mackin DM 

PROVIDER: S-EPMC10313752 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature