Ontology highlight
ABSTRACT:
SUBMITTER: Elahi FM
PROVIDER: S-EPMC10314118 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Elahi Fanny M FM Alladi Suvarna S Black Sandra E SE Claassen Jurgen A H R JAHR DeCarli Charles C Hughes Timothy M TM Moonen Justine J Pajewski Nicholas M NM Price Brittani R BR Satizabal Claudia C Shaaban C Elizabeth CE Silva Nárlon C B S NCBS Snyder Heather M HM Sveikata Lukas L Williamson Jeff D JD Wolters Frank J FJ Hainsworth Atticus H AH
Cell reports. Medicine 20230601 6
A large interventional trial, the Systolic Blood Pressure Intervention Trial sub-study termed Memory and Cognition in Decreased Hypertension (SPRINT-MIND), found reduced risk of cognitive impairment in older adults with intensive, relative to standard, blood-pressure-lowering targets (systolic BP < 120 vs. <140 mm Hg). In this perspective, we discuss key questions and make recommendations for clinical practice and for clinical trials, following SPRINT-MIND. Future trials should embody cognitive ...[more]