Longitudinal changes in pancreatic volume and pancreatic fat with weight gain in Japanese without diabetes: An analysis using health check-up data.

ABSTRACT:

Aims/introduction

There have been few reports about the longitudinal changes in pancreas volume (PV) or pancreatic steatosis (PS) in response to obesity. In this longitudinal analysis using health check-up data, we explored changes in PV, PS and glucose metabolic indices that occurred after weight gain in Japanese without diabetes.

Materials/methods

Clinical data on 37 Japanese subjects with a ≥1 kg/m² increase in body mass index between two health check-ups and without diabetes were collected. PV, pancreas attenuation (PA) and splenic attenuation (SA) were evaluated using computed tomography (CT) images. The pancreas area was outlined by hand in multiple images with slice thickness of 2 mm, and the PV was computed by summing these areas. PS was defined as the dif

SUBMITTER: Sunouchi M 

PROVIDER: S-EPMC10314282 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature