Implementation of point-of-care testing and prevalence of cryptococcal antigenaemia among patients with advanced HIV disease in Mumbai, India.

ABSTRACT:

Objectives

To describe the implementation of screening for cryptococcal antigenaemia by point-of-care (POC) serum cryptococcal antigen (CrAg) lateral flow assay, measure the prevalence and factors associated with serum cryptococcal antigenaemia in the routine programmatic setting.

Design

Cross-sectional study.

Setting

Seventeen publicly funded antiretroviral therapy (ART) centres in Mumbai, India.

Participants

Serum CrAg screening was offered to all adolescents (>10 years of age) and adults with advanced HIV disease (AHD) (CD4 <200 cells/mm³ or with WHO clinical stage III/IV) regardless of symptoms of cryptococcal meningitis.

Primary and secondary outcome measures

The primary outcome was to describe the implementation of serum CrAg screening a

SUBMITTER: Acharya S 

PROVIDER: S-EPMC10314426 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature