Inflammation associated with lung function abnormalities in COVID-19 survivors.

ABSTRACT:

Background

Activation of inflammatory pathways promotes organ dysfunction in COVID-19. Currently, there are reports describing lung function abnormalities in COVID-19 survivors; however, the biological mechanisms remain unknown. The aim of this study was to analyze the association between serum biomarkers collected during and following hospitalization and pulmonary function in COVID-19 survivors.

Methods

Patients recovering from severe COVID-19 were prospectively evaluated. Serum biomarkers were analyzed from admission to hospital, peak during hospitalization, and at the time of discharge. Pulmonary function was measured approximately 6 weeks after discharge.

Results

100 patients (63% male) were included (age 48 years, SD ± 14) with 85% having at least one comorbidity

SUBMITTER: Mancilla-Ceballos R 

PROVIDER: S-EPMC10314600 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature