Guided blood transfusion of trauma patients with rotational thromboelastometry: a single-center cohort study.

ABSTRACT:

Background

Rotational thromboelastometry (ROTEM) is a blood test used to measure in vitro clot strength as a surrogate for a patient's ability to form clots in vivo. This provides information about induction, formation, and clot lysis, allowing goal-directed transfusion therapy for specific hemostatic needs. We sought to evaluate the effect of ROTEM-guided transfusion on blood product usage and in-hospital mortality among patients with a traumatic injury.

Methods

This was a single-center observational cohort analysis of emergency department patients in a Level 1 trauma center. We compared blood usage in trauma patients in whom ratio-based massive hemorrhage protocols were activated in the twelve months before the introduction of ROTEM (pre-ROTEM group) to the twelve months f

SUBMITTER: Salehi M 

PROVIDER: S-EPMC10315024 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature