Tuberculosis in 0-5-year-old children following TB contact investigations: a retrospective study in a low burden setting.

ABSTRACT:

Introduction

We assessed the risk of tuberculosis (TB), the management and the outcomes of 0-5-year-old children after TB contact investigations in a low-burden setting.

Method

All 0-5-year-old children who attended the TB clinic of Robert Debre Hospital, Paris, France, for a TB contact investigation between June 2016 and December 2019 were included in this retrospective study. The risk factors for TB were assessed using univariate and multivariate analyses.

Results

A total of 261 children were included. Forty-six (18%) had TB, including 37 latent tuberculosis infections (LTBIs) and 9 active TB diseases. The prevalence of TB was 21% among high-risk contacts, i.e., household or close contacts and regular or casual contacts. There was no TB among intermediate- or low-ri

SUBMITTER: Pasqualini C 

PROVIDER: S-EPMC10315530 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature