Chronic traumatic encephalopathy neuropathologic change is uncommon in men who played amateur American football.

ABSTRACT:

Introduction

We examined postmortem brain tissue from men, over the age of 50, for chronic traumatic encephalopathy neuropathologic change (CTE-NC). We hypothesized that (i) a small percentage would have CTE-NC, (ii) those who played American football during their youth would be more likely to have CTE-NC than those who did not play contact or collision sports, and (iii) there would be no association between CTE-NC and suicide as a manner of death.

Methods

Brain tissue from 186 men and accompanying clinical information were obtained from the Lieber Institute for Brain Development. Manner of death was determined by a board-certified forensic pathologist. Information was obtained from next of kin telephone interviews, including medical, social, demographic, family, and psychia

SUBMITTER: Iverson GL 

PROVIDER: S-EPMC10315537 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature