Prognostic significance of increased preoperative red cell distribution width (RDW) and changes in RDW for colorectal cancer.

ABSTRACT:

Background

Increased preoperative red cell distribution width (RDW) is associated with poor prognosis in several cancers, but the relationships between preoperative RDW and changes in RDW (ΔRDW) and colorectal cancer (CRC) prognosis remain unclear. Our study aimed to demonstrate the prognostic significance of increased preoperative RDW and ΔRDW for CRC.

Methods

In this retrospective analysis, we enrolled 833 patients who underwent CRC surgery between 2015 and 2019 at the Affiliated Hospital of Xuzhou Medical University, China. ΔRDW in our study was defined as RDW at 1 month after discharge minus preoperative RDW. According to receiver operating characteristic (ROC) curve analysis, we used cut-off values of 13.5% for RDW, 0.9% for ΔRDW. The cumulative survival rate was determ

SUBMITTER: Lu X 

PROVIDER: S-EPMC10315724 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature