Association between localized retinal nerve fiber layer defects in nonglaucomatous eyes and metabolic syndrome: a propensity score-matched analysis

ABSTRACT:

Background

We investigated the association between metabolic syndrome and localized retinal nerve fiber layer (RNFL) defects in nonglaucomatous subjects.

Methods

We examined 20,385 adults who visited the Health Promotion Center of Seoul St. Mary’s Hospital between May 2015 and April 2016. After excluding those with known glaucoma or glaucomatous optic discs, subjects with and without localized RNFL defects were 1:5 propensity score matched. Metabolic syndrome components, including central obesity, elevated triglyceride, reduced high-density lipoprotein (HDL) cholesterol, elevated blood pressure (BP), and elevated fasting glucose, were compared between two groups. We performed logistic regression to investigate the association between RNFL defects and each component of met

SUBMITTER: Baek J 

PROVIDER: S-EPMC10316109 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature