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Fulminant Myocarditis: When One Size Does Not Fit All – A Critical Review of the Literature


ABSTRACT: Fulminant myocarditis, rather than being a distinct form of myocarditis, is instead a peculiar clinical presentation of the disease. The definition of fulminant myocarditis has varied greatly in the last 20 years, leading to conflicting reports on prognosis and treatment strategies, mainly because of varied inclusion criteria in different studies. The main conclusion of this review is that fulminant myocarditis may be due to different histotypes and aetiologies that can be diagnosed only by endomyocardial biopsy and managed by aetiology-directed treatment. This life-threatening presentation requires rapid, targeted management both in the short term (mechanical circulatory support, inotropic and antiarrhythmic treatment and endomyocardial biopsy) and in the long term (including prolonged fo

SUBMITTER: Giordani A 

PROVIDER: S-EPMC10316338 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature