Dataset Information

Incidence of second primary cancers in oral and pharyngeal cancer patients using a large medical claims database in Japan.

ABSTRACT:

Background/purpose

As the occurrence of second primary cancers (SPCs) is strongly related to the survival rate of patients with oral and pharyngeal cancers, early detection and treatment are important. Therefore, this study aimed to clarify the incidence of SPCs and their risk factors in patients with oral and pharyngeal cancer.

Materials and methods

This observational study was conducted using data from the administrative claims database of 21,736 participants with oral and pharyngeal cancer from January 2005 to December 2020. We evaluated the cumulative incidence of SPCs among patients with oral and pharyngeal cancers using the Kaplan-Meier method. The Cox proportional-hazard model was used for multivariate analysis.

Results

Of the 1633 patients with oral and pharyngeal cancer who qualified for analysis, 388 developed SPCs (incidence rate, 7.994/1000 person-months). The multivariate analysis showed that the risk of developing SPCs was affected by age at diagnosis of oral and pharyngeal cancer, cancer treatment, and anatomical site of the primary cancer.

Conclusion

Patients with oral and pharyngeal cancers are at a high risk of developing SPCs. The data from this study may be useful in providing accurate information to patients with oral and oropharyngeal cancer.

SUBMITTER: Matsui M

PROVIDER: S-EPMC10316450 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature

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Publications

Incidence of second primary cancers in oral and pharyngeal cancer patients using a large medical claims database in Japan.

Matsui Masanori M Kawamura Kahori K Kano Keita K Yoshimatsu Hideki H Doi Takashi T Miyake Tatsuro T

Journal of dental sciences 20221209 3

<h4>Background/purpose</h4>As the occurrence of second primary cancers (SPCs) is strongly related to the survival rate of patients with oral and pharyngeal cancers, early detection and treatment are important. Therefore, this study aimed to clarify the incidence of SPCs and their risk factors in patients with oral and pharyngeal cancer.<h4>Materials and methods</h4>This observational study was conducted using data from the administrative claims database of 21,736 participants with oral and phary ...[more]

PMID: 37404617

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Dataset Information

Incidence of second primary cancers in oral and pharyngeal cancer patients using a large medical claims database in Japan.

Background/purpose

Materials and methods

Results

Conclusion

Publications

Incidence of second primary cancers in oral and pharyngeal cancer patients using a large medical claims database in Japan.

Similar Datasets

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