Cardiopulmonary exercise testing before and after intravenous iron in preoperative patients: a prospective clinical study.

ABSTRACT:

Background

Anemia is associated with impaired physical performance and adverse perioperative outcomes. Iron-deficiency anemia is increasingly treated with intravenous iron before elective surgery. We explored the relationship between exercise capacity, anemia, and total hemoglobin mass (tHb-mass) and the response to intravenous iron in anemic patients prior to surgery.

Methods

A prospective clinical study was undertaken in patients having routine cardiopulmonary exercise testing (CPET) with a hemoglobin concentration ([Hb]) < 130 g^.l^-1 and iron deficiency/depletion. Patients underwent CPET and tHb-mass measurements before and a minimum of 14 days after receiving intravenous (i.v.) Ferric derisomaltose (Monofer®) at the baseline visit. Comparative analys

SUBMITTER: Plumb JOM 

PROVIDER: S-EPMC10316643 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature