Demographic, clinical and genetic factors associated with COVID-19 disease susceptibility and mortality in a Kurdish population.

ABSTRACT:

Background

Coronavirus disease 2019 (COVID-19) is a devastating pandemic that causes disease with a variability in susceptibility and mortality based on variants of various clinical and demographic factors, including particular genes among populations.

Objectives

Determine associations of demographic, clinical, laboratory, and single nucleotide polymorphisms in the ACE2, TMPRSS2, TNF-α, and IFN-γ genes to the incidence of infection and mortality in COVID-19 patients.

Design

Prospective cohort study SETTINGS: Various cities in the Kurdistan Region of Iraq.

Patients and methods

This prospective cohort study compared laboratory markers (D-dimer, tumor necrosis factor-alpha [TNF-α], interferon-gamma [IFN-γ], C-reactive protein [CRP], lymphocyte and ne

SUBMITTER: Smail SW 

PROVIDER: S-EPMC10317494 | biostudies-literature | 2023 May-Jun

REPOSITORIES: biostudies-literature