Characterization of clinical features and comorbidities between bipolar affective disorder with and without depressive episodes.

ABSTRACT:

Backgrounds

A proportion of patients with bipolar disorder (BD) manifests with only unipolar mania (UM). This study examined relevant clinical features and psychosocial characteristics in UM compared with depressive-manic (D-M) subgroups. Moreover, comorbidity patterns of physical conditions and psychiatric disorders were evaluated between the UM and D-M groups.

Methods

This clinical retrospective study (N = 1015) analyzed cases with an average of 10 years of illness duration and a nationwide population-based cohort (N = 8343) followed up for 10 years in the Taiwanese population. UM was defined as patients who did not experience depressive episodes and were not prescribed adequate antidepressant treatment during the disease course of BD. Logistic regression models adjusted f

SUBMITTER: Chang CE 

PROVIDER: S-EPMC10317814 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature