The place of new antibiotics for Gram-negative bacterial infections in intensive care: report of a consensus conference.

ABSTRACT:

Introduction

New beta-lactams, associated or not with beta-lactamase inhibitors (NBs/BIs), can respond to the spread of carbapenemase-producing enterobacteriales and nonfermenting carbapenem-resistant bacteria. The risk of emergence of resistance to these NBs/BIs makes guidelines necessary. The SRLF organized a consensus conference in December 2022.

Methods

An ad hoc committee without any conflict of interest (CoI) with the subject identified the molecules (ceftolozane-tazobactam, ceftazidime-avibactam, imipenem-cilastatin-relebactam, meropenem-vaborbactam and cefiderocol); defined 6 generic questions; drew up a list of subquestions according to the population, intervention, comparison and outcomes (PICO) model; and reviewed the literature using predefined keywords. The qual

SUBMITTER: Dequin PF 

PROVIDER: S-EPMC10317910 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature