Towards in vivo characterization of thyroid nodules suspicious for malignancy using multispectral optoacoustic tomography.

ABSTRACT:

Purpose

Patient-tailored management of thyroid nodules requires improved risk of malignancy stratification by accurate preoperative nodule assessment, aiming to personalize decisions concerning diagnostics and treatment. Here, we perform an exploratory pilot study to identify possible patterns on multispectral optoacoustic tomography (MSOT) for thyroid malignancy stratification. For the first time, we directly correlate MSOT images with histopathology data on a detailed level.

Methods

We use recently enhanced data processing and image reconstruction methods for MSOT to provide next-level image quality by means of improved spatial resolution and spectral contrast. We examine optoacoustic features in thyroid nodules associated with vascular patterns and correlate these directl

SUBMITTER: Noltes ME 

PROVIDER: S-EPMC10317911 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature