Comparison of Craniospinal Irradiation Using Proton Beams According to Irradiation Method and Initial Experience Treating Pediatric Patients

ABSTRACT:

Purpose

This study compared craniospinal irradiation using proton beam therapy (PBT) according to irradiation method and investigated the initial effects.

Methods and Materials

Twenty-four pediatric patients (1-24 years old) who received proton craniospinal irradiation were examined. Passive scattered PBT (PSPT) and intensity modulated PBT (IMPT) were used in 8 and 16 patients, respectively. The whole vertebral body technique was used for 13 patients <10 years old, and the vertebral body sparing (VBS) technique was used for the remaining 11 patients aged ≥10 years. The follow-up period was 17 to 44 (median, 27) months. Organ-at-risk and planning target volume (PTV) doses and other clinical data were examined.

Results

The maximum lens dose using IMPT was lower tha

SUBMITTER: Fukumitsu N 

PROVIDER: S-EPMC10318217 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature