Shared alterations in hippocampal structural covariance in subjective cognitive decline and migraine.

ABSTRACT:

Introduction

Subjective cognitive decline (SCD) and migraine are often comorbid. Hippocampal structural abnormalities have been observed in individuals with both SCD and migraine. Given the known structural and functional heterogeneity along the long axis (anterior to posterior) of the hippocampus, we aimed to identify altered patterns of structural covariance within hippocampal subdivisions associated with SCD and migraine comorbidities.

Methods

A seed-based structural covariance network analysis was applied to examine large-scale anatomical network changes of the anterior and posterior hippocampus in individuals with SCD, migraine and healthy controls. Conjunction analyses were used to identify shared network-level alterations in the hippocampal subdivisions in individuals

SUBMITTER: Tsai CL 

PROVIDER: S-EPMC10318340 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature