Gene expression of peripheral blood mononuclear cells and CD8⁺ T cells from gilts after PRRSV infection.

ABSTRACT: Porcine reproductive and respiratory syndrome virus (PRRSV) is a positive-stranded RNA virus, which emerged in Europe and U.S.A. in the late 1980s and has since caused huge economic losses. Infection with PRRSV causes mild to severe respiratory and reproductive clinical symptoms in pigs. Alteration of the host immune response by PRRSV is associated with the increased susceptibility to secondary viral and bacterial infections resulting in more serious and chronic disease. However, the expression profiles underlying innate and adaptive immune responses to PRRSV infection are yet to be further elucidated. In this study, we investigated gene expression profiles of PBMCs and CD8⁺ T cells after PRRSV AUT15-33 infection. We identified the highest number of differentially expressed gene

SUBMITTER: Lagumdzic E 

PROVIDER: S-EPMC10318438 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature