Mapping Lesion-Related Epilepsy to a Human Brain Network.

ABSTRACT:

Importance

It remains unclear why lesions in some locations cause epilepsy while others do not. Identifying the brain regions or networks associated with epilepsy by mapping these lesions could inform prognosis and guide interventions.

Objective

To assess whether lesion locations associated with epilepsy map to specific brain regions and networks.

Design, setting, and participants

This case-control study used lesion location and lesion network mapping to identify the brain regions and networks associated with epilepsy in a discovery data set of patients with poststroke epilepsy and control patients with stroke. Patients with stroke lesions and epilepsy (n = 76) or no epilepsy (n = 625) were included. Generalizability to other lesion types was assessed using 4 independ

SUBMITTER: Schaper FLWVJ 

PROVIDER: S-EPMC10318550 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature