Characteristics of glucose and lipid metabolism and the interaction between gut microbiota and colonic mucosal immunity in pigs during cold exposure.

ABSTRACT:

Background

Cold regions have long autumn and winter seasons and low ambient temperatures. When pigs are unable to adjust to the cold, oxidative damage and inflammation may develop. However, the differences between cold and non-cold adaptation regarding glucose and lipid metabolism, gut microbiota and colonic mucosal immunological features in pigs are unknown. This study revealed the glucose and lipid metabolic responses and the dual role of gut microbiota in pigs during cold and non-cold adaptation. Moreover, the regulatory effects of dietary glucose supplements on glucose and lipid metabolism and the colonic mucosal barrier were evaluated in cold-exposed pigs.

Results

Cold and non-cold-adapted models were established by Min and Yorkshire pigs. Our results exhibited that col

SUBMITTER: Teng T 

PROVIDER: S-EPMC10318708 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature