Serum creatinine/cystatin C ratio as a prognostic indicator for patients with colorectal cancer.

ABSTRACT:

Background

This study aimed to explore the relationship between creatinine/cystatin C ratio and progression-free survival (PFS) and overall survival (OS) in colorectal cancer (CRC) patients undergoing surgical treatment.

Methods

A retrospective analysis was conducted on 975 CRC patients who underwent surgical resection from January 2012 to 2015. Restricted three-sample curve to display the non-linear relationship between PFS/OS and creatinine-cystatin C ratio. Cox regression model and Kaplan-Meier method were used to evaluate the effect of the creatinine-cystatin C ratio on the survival of CRC patients. Prognostic variables with p-value ≤0.05 in multivariate analysis were used to construct prognostic nomograms. The receiver operator characteristic curve was used to compare t

SUBMITTER: Gao S 

PROVIDER: S-EPMC10319047 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature