Disease Attribution to Multiple Exposures Using Aggregate Data.

ABSTRACT:

Background

Identifying which exposures cause disease and quantifying their impacts is essential in promoting and monitoring public health. When multiple exposures are involved, measuring individual contributions becomes challenging.

Methods

The authors propose a disease attribution method based on aggregate data or summary statistics of individual-level data, possibly from multiple data sources.

Results

Using the proposed method, the burden of disease is apportioned to the independent and interaction effects of each of its major risk factors and all the other factors as a whole. This scheme guarantees that 100% is the total share of the burden.

Conclusion

The calculation is simple and straightforward; therefore, it is recommended for use in studies on disease b

SUBMITTER: Lee WC 

PROVIDER: S-EPMC10319529 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature