Survival impact of surgical site infection in esophageal cancer surgery: A multicenter retrospective cohort study.

ABSTRACT:

Aim

This study was performed to evaluate the oncological impact of surgical site infection (SSI) and pneumonia on long-term outcomes after esophagectomy.

Methods

The Japan Society for Surgical Infection conducted a multicenter retrospective cohort study involving 407 patients with curative stage I/II/III esophageal cancer at 11 centers from April 2013 to March 2015. We investigated the association of SSI and postoperative pneumonia with oncological outcomes in terms of relapse-free survival (RFS) and overall survival (OS).

Results

Ninety (22.1%), 65 (16.0%), and 22 (5.4%) patients had SSI, pneumonia, and both SSI and pneumonia, respectively. The univariate analysis demonstrated that SSI and pneumonia were associated with worse RFS and OS. In the multivariate analysis,

SUBMITTER: Matsuda A 

PROVIDER: S-EPMC10319607 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature