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Prognostic significance of osteosarcopenia in older adults with colorectal cancer.


ABSTRACT:

Aim

Osteopenia and sarcopenia, features of the aging process, are recognized as major health problems in an aging society. This study investigated the prognostic impact of osteosarcopenia, the coexistence of osteopenia and sarcopenia, in older adults undergoing curative resection for colorectal cancer.

Methods

We retrospectively reviewed data of older adults aged 65-98 y who had undergone curative resection for colorectal cancer. Osteopenia was evaluated by bone mineral density measurement in the midvertebral core of the 11th thoracic vertebra on preoperative computed tomography images. Sarcopenia was evaluated by measuring the skeletal muscle cross-sectional area at the third lumbar vertebra level. Osteosarcopenia was defined as the coexistence of osteopenia and sarcopenia.

SUBMITTER: Takano Y 

PROVIDER: S-EPMC10319614 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature