MULocDeep web service for protein localization prediction and visualization at subcellular and suborganellar levels.

ABSTRACT: Predicting protein localization and understanding its mechanisms are critical in biology and pathology. In this context, we propose a new web application of MULocDeep with improved performance, result interpretation, and visualization. By transferring the original model into species-specific models, MULocDeep achieved competitive prediction performance at the subcellular level against other state-of-the-art methods. It uniquely provides a comprehensive localization prediction at the suborganellar level. Besides prediction, our web service quantifies the contribution of single amino acids to localization for individual proteins; for a group of proteins, common motifs or potential targeting-related regions can be derived. Furthermore, the visualizations of targeting mechanism analyses can be

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC10320056 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature