Invasive candidiasis: current clinical challenges and unmet needs in adult populations.

ABSTRACT: Invasive candidiasis (IC) is a serious infection caused by several Candida species, and the most common fungal disease in hospitals in high-income countries. Despite overall improvements in health systems and ICU care in the last few decades, as well as the development of different antifungals and microbiological techniques, mortality rates in IC have not substantially improved. The aim of this review is to summarize the main issues underlying the management of adults affected by IC, focusing on specific forms of the infection: IC developed by ICU patients, IC observed in haematological patients, breakthrough candidaemia, sanctuary site candidiasis, intra-abdominal infections and other challenging infections. Several key challenges need to be tackled to improve the clinical management and

SUBMITTER: Soriano A 

PROVIDER: S-EPMC10320127 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature