ChroKit: a Shiny-based framework for interactive analysis, visualization and integration of genomic data.

ABSTRACT: We developed ChroKit (the Chromatin toolKit), an interactive web-based framework written in R that enables intuitive exploration, multidimensional analyses, and visualization of genomic data from ChIP-Seq, DNAse-Seq or any other NGS experiment that reports the enrichment of aligned reads over genomic regions. This program takes preprocessed NGS data and performs operations on genomic regions of interest, including resetting their boundaries, their annotation based on proximity to genomic features, the association to gene ontologies, and signal enrichment calculations. Genomic regions can be further refined or subsetted by user-defined logical operations and unsupervised classification algorithms. ChroKit generates a full range of plots that are easily manipulated by point and click operati

SUBMITTER: Croci O 

PROVIDER: S-EPMC10320144 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature