Molecular ecology of highest priority critically important antibiotic resistant Escherichia coli from mammals housed at an urban zoo.

ABSTRACT:

Objectives

Zoos are environments where species of highly valued animals are kept largely separated from others and the wider world. We report the molecular ecology of critically important antibiotic resistant (ABR) Escherichia coli carried by 28 mammalian species housed in a zoo located in an urban residential district.

Methods

Over 3 months we collected 167 faecal samples from captive mammals and processed for E. coli resistant to third-generation cephalosporins (3GC-R) and fluoroquinolones (FQ-R). Isolates were sequenced using Illumina.

Results

We identified high rates of faecal sample-level positivity, with 50%, 57% and 36% of mammalian species excreting 3GC-R, FQ-R or dual 3GC-R/FQ-R E. coli, respectively. Isolates represented multiple ST and ABR mechanisms; CTX-M

SUBMITTER: Sealey JE 

PROVIDER: S-EPMC10320166 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature