Usefulness of automatic assessment for longitudinal strain to diagnose wild-type transthyretin amyloid cardiomyopathy.

ABSTRACT:

Background

Left ventricular (LV) apical sparing by transthoracic echocardiography (TTE) has not been widely accepted to diagnose transthyretin amyloid cardiomyopathy (ATTR-CM), because it is time consuming and requires a level of expertise. We hypothesized that automatic assessment may be the solution for these problems.

Methods-and-results

We enrolled 63 patients aged ≥70 years who underwent ^99mTc-labeled pyrophosphate (^99mTc-PYP) scintigraphy on suspicion of ATTR-CM and performed TTE by EPIQ7G, and had enough information for two-dimensional speckle tracking echocardiography at Kumamoto University Hospital from January 2016 to December 2019. LV apical sparing was described as a high relative apical longitudinal strain (LS) index (RapLSI). Measurement o

SUBMITTER: Usuku H 

PROVIDER: S-EPMC10320495 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature