Vitamin D supplementation for depression in older adults: a meta-analysis of randomized controlled trials.

ABSTRACT:

Background

In older adults, depression is associated with several other clinical problems such as cognitive impairment and low quality of life. Several studies have evaluated the relationship between vitamin D and depression in older adults; however, the results have been controversial thus far.

Objective

This study aimed to investigate the effects of vitamin D supplementation on depressive symptom improvement among individuals aged ≥60 years with or without a diagnosis of depression or depressive symptoms based on a meta-analysis of randomized controlled trials (RCTs).

Methods

RCTs were identified to analyze the relationship between vitamin D supplementation and depressive symptoms. MEDLINE, CENTRAL, Embase, and PsycINFO were systematically searched for relevant arti

SUBMITTER: Park Y 

PROVIDER: S-EPMC10320579 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature