Trends in tuberculosis clinicians' adoption of short-course regimens for latent tuberculosis infection.

ABSTRACT:

Objective

Little is known about regimen choice for latent tuberculosis infection in the United States. Since 2011, the Centers for Disease Control and Prevention has recommended shorter regimens-12 weeks of isoniazid and rifapentine or 4 months of rifampin-because they have similar efficacy, better tolerability, and higher treatment completion than 6-9 months of isoniazid. The objective of this analysis is to describe frequencies of latent tuberculosis infection regimens prescribed in the United States and assess changes over time.

Methods

Persons at high risk for latent tuberculosis infection or progression to tuberculosis disease were enrolled into an observational cohort study from September 2012-May 2017, tested for tuberculosis infection, and followed for 24 months. Thi

SUBMITTER: Feng PI 

PROVIDER: S-EPMC10320582 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature