Optimal fractionation and timing of weekly cone-beam CT in daily surface-guided radiotherapy for breast cancer.

ABSTRACT:

Purpose

Surface-guided radiotherapy (SGRT) has been demonstrated to be a promising supplement to cone-beam computed tomography (CBCT) in adjuvant breast cancer radiotherapy, but a rational combination mode is lacking in clinical practice. The aim of this study was to explore this mode and investigate its impact on the setup and dose accuracy.

Methods and materials

Daily SGRT and weekly CBCT images were acquired for 23 patients with breast cancer who received conventional fractionated radiotherapy after lumpectomy. Sixteen modes were acquired by randomly selecting one (CBCT₁), two (CBCT_ij), three (CBCT_ijk), four (CBCT_ijkl), and five (CBCT₁₂₃₄₅) images from the CBCT images for fusion with the SGRT. The CTV-PTV margins, OAR

SUBMITTER: Peng H 

PROVIDER: S-EPMC10320897 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature