Open source code for the generation of digital reference objects for dynamic contrast-enhanced MRI analysis software validation.

ABSTRACT:

Objectives

Dynamic contrast-enhanced MR images can be analyzed through the application of a wide range of kinetic models. This process is prone to variability and a lack of standardization that can affect the measured metrics. There is a need for customized digital reference objects (DROs) for the validation of DCE-MRI software packages that undertake kinetic model analysis. DROs are currently available only for a small subset of the kinetic models commonly applied to DCE-MRI data. This work aimed to address this gap.

Methods

Code was written in the MATLAB programming environment to generate customizable DROs. This modular code allows the insertion of a plug-in to describe the kinetic model to be tested. We input our generated DROs into three commercial and open-source analy

SUBMITTER: Gill AB 

PROVIDER: S-EPMC10321261 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature