Multidimensional MRI for Characterization of Subtle Axonal Injury Accelerated Using an Adaptive Nonlocal Multispectral Filter.

ABSTRACT: Multidimensional MRI is an emerging approach that simultaneously encodes water relaxation (T₁ and T₂) and mobility (diffusion) and replaces voxel-averaged values with subvoxel distributions of those MR properties. While conventional (i.e., voxel-averaged) MRI methods cannot adequately quantify the microscopic heterogeneity of biological tissue, using subvoxel information allows to selectively map a specific T₁-T₂-diffusion spectral range that corresponds to a group of tissue elements. The major obstacle to the adoption of rich, multidimensional MRI protocols for diagnostic or monitoring purposes is the prolonged scan time. Our main goal in the present study is to evaluate the performance of a nonlocal estimation of mul

SUBMITTER: Benjamini D 

PROVIDER: S-EPMC10321473 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature