Weight Matching in Infant Heart Transplantation: A National Registry Analysis.

ABSTRACT:

Background

Infants account for a significant proportion of pediatric heart transplantation but also suffer from a high waitlist mortality. Donor oversizing by weight-based criteria is common practice in transplantation and is prevalent in this group. We sought to analyze the impact of oversizing on outcomes in infants.

Methods

Infant heart transplantations reported to the United Network for Organ Sharing from January 1994 to September 2019 were retrospectively analyzed. 2384 heart transplantation recipients were divided into quintiles (Q1-Q5) on the basis of donor-to-recipient weight ratio (DRWR). Multivariate Cox regression was used to estimate the effect of DRWR. The primary end point was graft survival at 1 year.

Results

The median DRWR for each quintile was 0.90 (

SUBMITTER: Lee JY 

PROVIDER: S-EPMC10321673 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature