Left ventricular strain and myocardial work in apical hypertrophic cardiomyopathy.

ABSTRACT:

Background

Apical hypertrophic cardiomyopathy (ApHCM) is recognized for its associated cardiovascular morbidity. Herein we describe left ventricular (LV) function and mechanics over long-term follow-up in ApHCM.

Methods

A retrospective study of 98 consecutive ApHCM patients was performed (mean age: 64±15 years, 46% female) using 2D and speckle-tracking echocardiography. LV function and mechanics were characterized by global longitudinal strain (GLS), segmental strain, and myocardial work indices. Myocardial work was calculated by integrating longitudinal strain and blood pressure as estimated by the brachial artery cuff pressure, to generate an LV pressure-strain loop with adjusted ejection and isovolumetric periods. Composite complications were defined as all-cause mortalit

SUBMITTER: Mihos CG 

PROVIDER: S-EPMC10323562 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature