Siblings with Gorlin-Goltz syndrome associated with cardiac tumors: a case report and review of literature.

ABSTRACT: Primary cardiac tumors in children are very rare and may be associated with severe arrhythmias and sudden infant death syndrome. These cardiac arrhythmias vary depending on the location and size of the tumor. Sixty-four percent of children with cardiac fibroma, the second most common benign cardiac tumor in children, have ventricular arrhythmias, affecting therapeutic management and risk profile of these children. We report on two siblings with cardiac fibromas whose clinical presentations differed depending on their locations and size of the tumors. The first child, a three-year-old girl, was diagnosed with a cardiac fibroma in the left ventricle at the age of 8 months after surviving resuscitation due to ventricular fibrillation. Secondary prophylactic implantation of an ICD was performe

SUBMITTER: Wilke PI 

PROVIDER: S-EPMC10324108 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature