Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer.

ABSTRACT: Breast cancer is the second leading cause of death for women worldwide. The heterogeneity of this disease presents a big challenge in its therapeutic management. However, recent advances in molecular biology and immunology enable to develop highly targeted therapies for many forms of breast cancer. The primary objective of targeted therapy is to inhibit a specific target/molecule that supports tumor progression. Ak strain transforming, cyclin-dependent kinases, poly (ADP-ribose) polymerase, and different growth factors have emerged as potential therapeutic targets for specific breast cancer subtypes. Many targeted drugs are currently undergoing clinical trials, and some have already received the FDA approval as monotherapy or in combination with other drugs for the treatment of different f

SUBMITTER: Ye F 

PROVIDER: S-EPMC10324146 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature